As human rights organizations, scholars, defenders and activists, we the 167 undersigned, write to express our grave concern about the work of the U.S. State Department’s Commission on Unalienable Rights and any potential report or output that undermines the international human rights system and purports to reinterpret its respective treaties and monitoring bodies. In particular, we urge the Commission to reject the prioritization of freedom of religion as a cloak to permit violations of the human rights of women, girls, and lesbian, gay, bisexual and transgender (LGBT) people. Now more than ever, countries worldwide should prioritize the rights to health and well-being of all their people without discrimination and recognize that reproductive rights are clearly established and articulated under international law. These rights are interrelated and indivisible from all human rights and cannot be subordinated within a hierarchy of rights.